RALA and metastatic neoplasm: Age greater than 16 years (HR = 2.589, 95% CI: 1.341-4.997, p = 0.005), metastatic tumors (HR = 2.070, 95% CI: 1.043-4.109, p = 0.037), and high expression of RALA (HR = 3.764, 95% CI: 1.674-8.462, p = 0.001) all increased the overall risk of survival, while surgical treatment (limb sparing, HR = 0.141, 95% CI: 0.038-0.515, p = 0.003; amputation, HR = 0.041, 95% CI: 0.007-0.233, p < 0.001) was associated with decreased mortality (Figure 5(h)).