After conducting functional enrichment analysis of females’ gene list, genes with SNPs p < 0.00018 have shown a link to certain diseases including systemic lupus erythematosus disease (SLE; 5 Genes; p = 0.004400769; BRD2, OR12D2, CR2, OR5V1, HLA-DOA), Amyotrophic Lateral Sclerosis (3 Genes; p = 0.046868501; CUBN, SIPA1L2, COMMD10), as well as some pathways like regulation of complement cascade (2 Genes; p = 0. The gene discussed is CR2; the disease is systemic lupus erythematosus.