Moreover, the concentrations of sodium, albumin, and hemoglobin were significantly lower in the ESRD group than in the other two groups [sodium: 138.10 ± 2.54, 140.13 ± 2.39, and 140.73 ± 3.80 mEq/L (p < 0.05); albumin: 4.03 ± 0.34, 4.33 ± 0.42, and 4.23 ± 0.32 g/dL (p < 0.05); and hemoglobin: 10.95 ± 1.21, 13.17 ± 1.39, and 11.72 ± 2.19 g/dL, (p < 0.05) in the ESRD, control, and CKD groups, respectively]. This evidence concerns the gene ALB and chronic kidney disease.