We also performed random- and fixed-effects models to evaluate the hazard ratio (HR) and 95% confidence interval (CI), respectively.<h4>Result</h4>The result of our meta-analysis shows that elevated CRP levels were related to worse overall survival (OS) (HR = 1.752, 95% CI = 1.304-2.355, <i>p</i> = 0.000), cancer-specific survival (CSS) (HR = 1.663, 95% CI = 1.064-2.6, <i>p</i> = 0.026), and progression-free survival (PFS) (HR = 1.663, 95% CI = 1.064-2.6, <i>p</i> = 0.026) of PCa patients. Here, CRP is linked to posterior cortical atrophy.