MAP2K7 and cancer: Consistent with all this, the authors of the study found that the in vitro treatment of βTC-3 cancer cells with MK-801 induced the activation of both MEK-MAPK and CaMK signaling pathways, probably because in cell conditions, the proliferation, anti-apoptotic, and invasion occur within a relatively short period (72 hours) allowing the activation of proliferation and invasion at the same time (Figure 3).