As a result, Ect4 mutant flies exhibit increased susceptibility to infection by DCV, whereas overexpression of Ect4 confers resistance against DCV infection; Ect4 regulates the expression of JAK/STAT pathway target genes TotA and TotM; Ect4 interacts with Stat92E to alter the tyrosine phosphorylation status of Stat92E. This evidence concerns the gene SOAT1 and infection.