used a weighted co-expression network to analyze and establish 15 mRNAs, including NLRC4, as hub genes of the mRNA-lncRNA-pathway network related to sepsis, and the expression of these genes was up-regulated in sepsis patients (33) Salmonella typhimurium is a Gram-negative pathogen that causes diseases ranging from gastroenteritis to systemic infections and sepsis. The gene discussed is NLRC4; the disease is Sepsis.