IL6 and COVID-19: CRS in COVID-19 patients has been reported to induce many pro-inflammatory mediators, including TNF, monocyte chemoattractant protein-1a (MCP-1), inducible protein 10 (IP-10), IFN-α, GM-CSF, interleukin (IL)-1, IL-2, IL-6, and IL-7 (8–12).