As shown in Figure 2, the serum of ALT (Figure 2A), AST (Figure 2B), AST/ALT ratio (Figure 2C), bilirubin (Figure 2D), GGT (Figure 2E) and CRP (Figure 2F), which are the most common markers of liver injury, were all higher in pre-diabetes compared to normal control subjects. The gene discussed is CRP; the disease is diabetes mellitus.