CRP and rheumatoid arthritis: RNA sequencing and qPCR validation analysis showed that lnc-AL928768.3 and lnc-AC091493.1 expression levels were elevated in the synovial tissues of RA patients and positively correlated with DAS28-ESR and CRP, which when combined with ROC curve analysis suggested that they are good biomarkers for predicting RA risk and disease activity (151).