IL37 and rheumatoid arthritis: Furthermore, in a validation cohort of 598 patients comprising 230 RA patients, this finding suggested a higher specificity of IL-37 in identifying RA compared with patients with OA (AUC = 0.87), systemic lupus erythematosus (SLE) (0.86), gout (0.91), ankylosing spondylitis (AS) (0.92), and primary Sjögren’s syndrome (pSS) (0.87) (65).