For example, IL-6 or tumor-related factors can induce the overexpression of lnc C/EBPβ, LNC-CHOP, Olfr29-ps1, Pvt1 and RNCR3 in MDSCs, while chronic and low-dose stimulation of inflammation and tumor factors can also promote the down-regulation of lncRNAs. This evidence concerns the gene PVT1 and neoplasm.