Recent data show that HOTAIRM1 is a lncRNA that is abnormally active in different tumours and is related to hepatocellular carcinoma, colorectal, gastric, head and neck, ovarian, thyroid cancers, etc (101).Some authors detected that HOTAIRM1 expression was significantly reduced in tumour tissues. The gene discussed is HOTAIRM1; the disease is hepatocellular carcinoma.