IFNA1 and myeloid sarcoma: Yet, other studies found that IFN-α induces endothelial proliferation (97, 98) and that IFN-β signaling in endothelial cells has anti-inflammatory roles by inhibiting intracellular signaling of proinflammatory pathways and promoting BBB integrity in the host response to viruses and in MS (23, 99, 100).