Besides, Th17 cells are potent inducers of matrix metalloproteinase 1 (MMP1) and MMP3 (56), and a study has shown that SS is related to disorders of MMP3/tissue inhibitor of metalloproteinase 1 (TIMP1) and MMP9/TIMP1 ratios (57). This evidence concerns the gene TIMP1 and synovial sarcoma.