A recent study used reactive oxygen species (ROS) and N-acetylcysteine (NAC) to induce or block the expression of ICAM-1 and PD-L1 and revealed that the IFN signature that regulates the expression of ICAM-1 and PD-L1 in SS was related to oxidative stress (43–45). Here, IFNA1 is linked to synovial sarcoma.