It has been reported that high PRMT7 expression was associated with a lower risk of persistent kidney injury caused by antibiotics (Zheng et al., 2005), and PRMT1 expression was upregulated in renal epithelial cells of DN mice (Chen et al., 2019) as well as in podocytes of patients with DN (Zhu, 2018). This evidence concerns the gene PRMT1 and liver dysplastic nodule.