PRMT1 and Hepatic fibrosis: Found that the expression of PRMT1 was elevated in cirrhotic livers from human patients and in fibrotic livers of the mouse models, and the application of a selective inhibitor of PRMT1, PT1001B, or hepatic stellate cells (HSC)-specific PRMT1 knockout attenuated HSC activation and liver fibrosis in fibrotic models.