Furthermore, we observed reduced amounts of IFN-γ and TNF in the supernatants of palbociclib-treated PSCA-specific UniCAR T cells and CD3-PSCA bsAb-engaged T cells co-cultured with prostate cancer cells, which is caused by the palbociclib-mediated decrease in T cell numbers. The gene discussed is IFNG; the disease is prostate carcinoma.