PDX1 and type 1 diabetes mellitus: The results of RT-qPCR showed that the levels of islet function-related genes, such as Ins1, Glut2, and Pdx1 were significantly lowered compared with control group, and Allicin (L) or Allicin (H) administration could significantly up-regulate these gene levels in STZ-induced T1DM mice (Figure 3C).