BCL2 and type 1 diabetes mellitus: Meanwhile, the RT-qPCR result showed that the level of apoptosis gene Bax was up-regulated and the expression of anti-apoptosis gene Bcl-2 was down-regulated in T1DM group, and allicin treatment could reverse this trend in STZ-induced Min6, while AMPK inhibitor CC could abrogate the effect of allicin (Figure 6C).