GSEA results of KEGG analysis indicated that NNMT was associated with many cancer-promoting and immune-related pathways, such as the PI3K-Akt signaling pathways, cell adhesion molecules, and chemokine signaling pathways in COAD, HNSC, OV, and STAD; MAPK signaling pathways in HNSC, OV, and STAD; and cytokine-cytokine receptor interaction in COAD and OV (Figure 6(b)). The gene discussed is AKT1; the disease is cancer.