Meanwhile, co-expression of PKCδ and NDRG1 downregulated the mesenchymal marker N-cadherin, Vimentin, and Snail expression and upregulated the epithelial marker E-cadherin (Figures 7A, B), indicating that PKCδ may enhance the invasion and migration ability of CRC cells by inhibiting NDRG1 to promote EMT. This evidence concerns the gene PRKCD and colorectal carcinoma.