After comparing the exosomes from the plasma of thin and normal Bactrian camels, it was found that the identified 40 DE-miRNAs and 172 DEPs may be involved in the HCC progression, and normal Bactrian camel plasma-derived exosomes may repress tumor growth of HCC by Ras, Rap1, PI3K-Akt, MAPK, AMPK, FoxO, HIF-1, interleukin-1, and canonical Wnt signaling pathways. Here, AKT1 is linked to hepatocellular carcinoma.