Novel intraoperative molecular imaging methods with high sensitivity, specificity, distinguishability, and safety, such as 111In labeled PSMA, have been shown to locate the PCa lesions precisely (3); indocyanine green (ICG), a USA Food and Drug Administration (FDA)-approved near-infrared (NIR) fluorescent agent for highlighting tissue, has been combined with 99mTc to directly and accurately recognize malignant PCa tissue and metastases to assist decision making by surgeons during operations (4). This evidence concerns the gene FOLH1 and posterior cortical atrophy.