At present, studies have shown that NUDT21 is involved in the occurrence and development of many kinds of tumors, including glioblcomplementarily astoma (13), cervical cancer (14), breast cancer (15, 16), bladder cancer (17), pancreatic ductal adenocarcinoma (18), small cell lung cancer (19), gastric tumorigenesis (20). The gene discussed is NUDT21; the disease is breast cancer.