Moreover, miR-204, miR-1246, miR-145, miR-125a/b, and miR-146a, which are overexpressed or overcirculated in the TME of BC, target the proteins involved in STAT3 pathways, such as JAK2, IL-6R, C-Met, IGF1R, and ZEB1.9 Here, STAT3 is linked to breast cancer.