Based on these findings, we designed coumarinswith different alkylchain lengths as hybrid molecules with monoterpene compounds, suchas thymol, carvacrol, and so forth, which are potential CAIs.18 After the CA inhibitions of the obtained compoundswere determined, we examined the potential of the compounds to bedeveloped as antitumor agents by selecting the cancer cell lines thatwere the most expressed CA IX and XII isoforms. The gene discussed is CA9; the disease is cancer.