The expression of FGD genes, a gene family comprising FGD6, were analyzed to predict the OS of head and neck squamous cell carcinoma (HNSC) (44), in which the OS was positively related to high expression of FGD2 and FGD3 but not FGD6. The favorable effect of FGD6 on prognosis in DLBCL needs further investigation. Here, FGD3 is linked to head and neck squamous cell carcinoma.