Some well-studied lncRNAs such as HOX Transcript Antisense RNA (HOTAIR), X-Inactive Specific Transcript (XIST), and Nuclear Enriched Abundant Transcript1 (NEAT1) [5–7] demonstrated to participate in tumor progression, including regulating cell proliferation, cell cycle, apoptosis, and metastasis. The gene discussed is XIST; the disease is neoplasm.