CXCR4 and neoplasm: Association between CXCR4 expression and OS clinicopathological features was found significant on metastasis (OR = 4.01, 95%CI = 1.58–10.18; p = 0.003), stage (stage III & IV vs I & II, OR = 6.52, 95%CI = 1.05–40.62; p = 0.04), and tumor primary site (femur/tibia vs other, OR = 1.60, 95%CI = 1.04–2.45; p = 0.03), but not associated with histological type, gender, and age.