Pathogenic mutation rate of ATM was significantly higher among aggressive bladder cancer patients (7/208 = 3.37%) than nonaggressive bladder cancer patients (4/1487 = 0.27%), OR = 12.91 (95% CI: 3.71–44.50), p = 8.15E‐05. The gene discussed is ATM; the disease is urinary bladder carcinoma.