Mutations of the PAX6 gene may induce various ocular abnormalities, including congenital aniridia, anterior segment dysgenesis (ASD), cataract, corneal opacification, glaucoma, hypoplasia of the fovea and optic nerve, and nystagmus, leading to reduced visual acuity and even blindness (You et al., 2020). Here, PAX6 is linked to aniridia.