IDH1 and glioblastoma: Kaplan-Meier curves revealed that GBM in the low-risk cluster always had a longer OS than in the high-risk group, and p< 0.001 in the subcluster of age younger than 60, p = 0.005 in the subcluster of age older than 60, p< 0.001 in subcluster of male, p = 0.015 in subcluster of female, p< 0.001 in subcluster of IDH1 mutation, and p = 0.003 in subcluster of IDH1 wild-type (Figures 9D–I).