Similarly, DNMT3B and SRCAP variants have also been linked to neurodegenerative disorders, including Alzheimer’s disease (AD), PD, and amyotrophic lateral sclerosis (ALS) (Chesi et al., 2013; de Bem et al., 2016; Chen et al., 2017; Pezzi et al., 2017; Vardarajan et al., 2017). This evidence concerns the gene DNMT3B and amyotrophic lateral sclerosis.