Moreover, the Kaplan–Meier plotter data revealed that the patients with both high E2F8 mRNA levels and decreased T cells (CD4+ T cells, CD8+ T cells, and macrophage cells) had a worse RFS compared with the patients with enriched CD4+ T cells in breast invasive carcinoma (Figure 4C). This evidence concerns the gene E2F8 and invasive breast carcinoma.