More specifically, the expressions of CREBBP, EP300, TAF1, KAT6A, YEATS2, and SIRT1 and KAT2A, KAT8, HDAC1, HDAC2, HDAC3, and HDAC8 were significantly correlated with each other in HNSCC (Figure 3(c)). The gene discussed is YEATS2; the disease is head and neck squamous cell carcinoma.