Zhou et al. (2020) investigated lncRNAs and miRNAs in HCC and found that LINC003355:8 enhanced cell proliferation, migration, and invasion, whereas miR-6777-3p reduced proliferation, migration, and invasion. They identified WNT10B as a target of miR-6777-3p and that LINC00355:8 activates WNT10B by sponging miR-6777-3p to increase the expression of WNT signaling proteins β-catenin and c-MYC and inducing epithelial-to-mesenchymal transition markers (Table 1) (Zhou et al., 2020). This evidence concerns the gene WNT10B and hepatocellular carcinoma.