BCAP31 and cancer: It may also be noted that, relative to the corresponding non-cancerous tissues, BAP31 is generally highly upregulated in cancer, and it is expressed by many commonly used cell lines (such as HeLa, HEK293, CHO, COS-7 and BHK-21) (Lambert et al., 2001; Wakana et al., 2008; Wang et al., 2008).