NFKB1 and acute kidney injury: Ginsenoside Rg2 and Rh1 can regulate AKI by blocking LPS-TLR4 signaling, which reduces p38-STAT1 activation and NF-κB translocation, which in turn suppresses the transcription of inflammatory cytokines and mediators, such as IFN-β, TNF-α, IL-1β, and iNOS (Huynh, et al. 2020).