Ginsenoside CK can modulate primary glomerulonephritis by inhibiting NLRP3 inflammasome activation in renal tissue, macrophages, and bone marrow-derived dendritic cells, increasing SIRT1 expression, and triggering autophagy-mediated inhibition of NLRP3 inflammable bodies (Wu, et al. 2020). This evidence concerns the gene NLRP3 and glomerulonephritis.