Previous studies suggested that TPST1 upregulated expression levels in BLCA, breast cancer, tongue squamous cell carcinoma, and nasopharyngeal carcinoma [41, 42, 43, 44] and has a significant impact on the invasion and metastasis of hypopharyngeal cancer and colorectal cancer [45, 46]. The gene discussed is TPST1; the disease is colorectal cancer.