MAPT and Alzheimer disease: Figure 4 (top panel) shows the topography (mean tau SUVR) of the discrete tau-PET patterns at baseline (N=173): typical AD pattern had elevated tau-PET SUVR in the medial temporal lobe and in the remaining cortex; limbic predominant pattern had elevated tau-PET SUVR in the entorhinal cortex compared to the remaining cortex; cortical predominant pattern had elevated tau-PET SUVR in the neocortex compared to the entorhinal cortex; minimal tau pattern did not show marked elevation of tau-PET SUVR in any region.