MAPT and Alzheimer disease: Compared to the discrete-scale characterization of the tau-PET patterns which force-classifies each case into one of four categories (typical AD, limbic predominant, cortical predominant, minimal tau), the continuous-scale characterization additionally provides information on the extent of typicality and severity of each individual relative to others, thus, disentangling subtypes from disease stage, which could better inform the design of future clinical trials.