Kidney IL-6, IL-1β, and TNF-α (60.13 ± 7.54, 30.55 ± 2.86 and 116.97 ± 17.29 pg/mL, respectively) levels were significantly increased in RM-AKI model in comparison with control group (P < 0.01). The gene discussed is IL1B; the disease is acute kidney injury.