As shown in Fig. 3D, the γ-H2AX levels decreased more rapidly in CNE1-OE cells and 5-8F-NC cells than in CNE1-VEC control cells and 5-8F-shFLI1 cells respectively, indicating that FLI1 facilitated DNA lesion repair in NPC cells. Here, H2AX is linked to nasopharyngeal carcinoma.