Consequently, miR-155 is shown to be overexpressed in malignancy, boosting Cyclin D2 and lowering BCL6 expression directly.37, 38Upregulated levels of expression of miR-155 along with miR-21 was observed in premalignant lesions and invasive pancreatic cancers compared to the normal tissues.19miR-199a-5p, on the other hand, is downregulated in human OSCC tissues and cell lines, and its expression is lower in OSCC tissues with lymph node metastasis compared to tissues without lymph node metastasis. Here, BCL6 is linked to familial pancreatic carcinoma.