Briefly, we introduced the melanoma antigen recognized by T cell (MART-1)-specific T cell receptor (TCR; 1D3 clone) recognizing the human leukocyte antigen (HLA)-A2-restricted MART-1 peptide (amino acid [aa] 26–35) into CD8+ T lymphocytes isolated from blood of healthy donors.16 Here, CD8A is linked to melanoma.