We used a widely used C. elegans PD model (Fig. 3, B and C), the baIn11 strain (Pdat-1::α-syn/Pdat-1::GFP) (7), in which human α-synuclein (α-syn), an aggregation-prone protein associated with PD (32), and GFP are coexpressed under the control of the dat-1 gene promoter through an integrated transgene. The gene discussed is SLC6A3; the disease is Parkinson disease.