Assessment of the expression levels of these phosphatases in all 183 patients with MDS, or in the 135 RA and RAEB patient subset, revealed a trend toward anticorrelation between the expression of PTEN and INPP5D (SHIP1), while PTEN and INPP4B expression appear to be positively correlated (fig. The gene discussed is PTEN; the disease is myelodysplastic syndrome with single lineage dysplasia.