To further confirm whether CDC42 K153 maintains a low level of acetylation in human CRC tissues, we collected 69 pairs of CRC tissues and adjacent normal tissues from CRC patients presented with different tumor stages, including 18 tissue pairs of patients in stage I, 19 tissue pairs of patients in stage II, 26 pairs of patients in stage III, and 6 pairs of patients in stage IV. This evidence concerns the gene CDC42 and colorectal carcinoma.