We used quantitative real-time PCR (qPCR) to determine the expression level of mmp-2, mmp-9 and e-cadherin in HCT116 cells during Salmonella infection and found that the expression level of mmp-2 and e-cadherin decreased, while the expression level of mmp-9 increased significantly (Fig 6F). Here, CDH1 is linked to Salmonella Infections.