To investigate the oncogenic effects of the RNF38-RAD51B fusion, we cloned the fusion gene and established RNF38-RAD51B overexpressing LoVo (human colon adenocarcinoma cell line) and HCT116 (human rectum adenocarcinoma cell line) cells (S12 Fig). This evidence concerns the gene RNF38 and rectum adenocarcinoma.