B2M and familial pancreatic carcinoma: Three (B2M, CIP2A, and BCL2L1) of the twelve genes that were identified as upregulated in pancreatic cancer tissue from Black patients as compared to White patients that are associated with the PD1 pathway (Fig 4B) were associated with an increase in the hazard ratio (ratio > 2) for overall survival and a decrease in median survival (Fig 5A and S6 Table).