Among these genes, C-C chemokine receptor type 7 (CCR7) encodes the protein CCR7, which is a member of the G protein-coupled receptor (GPR) family and expressed in various activated B and T lymphocytes, and has lower expression in nonresponders compared to responders involved in therapy resistance of AML which is revealed by a recent study [39]. Here, ALDH18A1 is linked to acute myeloid leukemia.