Among these genes, C-C chemokine receptor type 7 (CCR7) encodes the protein CCR7, which is a member of the G protein-coupled receptor (GPR) family and expressed in various activated B and T lymphocytes, and has lower expression in nonresponders compared to responders involved in therapy resistance of AML which is revealed by a recent study [39]. The gene discussed is CCR7; the disease is acute myeloid leukemia.