NLGN3 belongs to the neuroligin family, a class of postsynaptic cell adhesion molecules that regulate synapse organization (Uchigashima et al., 2021) and dendritic outgrowth (Xu et al., 2019), and NLGN3 missense variants have previously been associated with autistic spectrum disorder (ASD) (Nguyen et al., 2020). The gene discussed is NLGN3; the disease is autism spectrum disorder.