The higher expression of REST total protein in the primary tissues of breast cancer (tumor 125 and normal 18, P < 0.01), ovarian cancer (tumor 100 and normal 25, P < 0.001), GBM (tumor 99 and normal 10, P < 0.001), UCEC (tumor 100 and normal 31, P < 0.001) and LUAD (tumor 111 and normal 111, P < 0.001) than in normal tissues was shown by the results of the CPTAC dataset (Fig. 1C). This evidence concerns the gene REST and ovarian cancer.