REST and neoplasm: These results confirmed miR-9-5p and miR-105-5p as the most potential tumor suppressive miRNAs of REST in adult type diffuse glioma, which included IDH-mutant, 1p/19q codeleted oligodendroglioma; IDH-mutant, non-codeleted astrocytoma; and IDH-wildtype glioblastoma35.