They are also typically positive for CK7, CK20, Uroplakin III, AR (Androgen receptor) and AKR1C while negative for PAX2 and PAX8 (markers of mullerian differentiation), Calretinin and inhibin (markers of stromal ovarian neoplasms), and SALL4 (a germ cell tumor marker) [7,28]. The gene discussed is UPK3A; the disease is ovarian neoplasm.